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Article

Molecular diagnostic criteria of myeloproliferative neoplasms.

Expert review of molecular diagnostics - 1 Jan 2000

Andrews Claire, Conneally Eibhlin, Langabeer Stephen E

Abstract excerpt

INTRODUCTION: Myeloproliferative neoplasms (MPN) are a heterogeneous group of clonal hematopoietic stem cell neoplasms characterized by the driver mutations JAK2, CALR, and MPL. These mutations cause constitutive activation of JAK-STAT signaling, which is central to pathogenesis of MPNs. Next-generation sequencing has further expanded the molecular landscape allowing for improved diagnostics, prognostication, and...

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PMID: 37999991
DOI: 10.1080/14737159.2023.2277370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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