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Article

Sphingolipid metabolism correlates with cerebrospinal fluid Beta amyloid levels in Alzheimer's disease.

PloS one - 1 Jan 2015

Fonteh Alfred N, Ormseth Cora, Chiang Jiarong, Cipolla Matthew, Arakaki Xianghong, Harrington Michael G

Abstract excerpt

Sphingolipids are important in many brain functions but their role in Alzheimer's disease (AD) is not completely defined. A major limit is availability of fresh brain tissue with defined AD pathology. The discovery that cerebrospinal fluid (CSF) contains abundant nanoparticles that include synaptic vesicles and large dense core vesicles offer an accessible sample to study these organelles, while the supernatant...

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Identifiers

PMID: 25938590
DOI: 10.1371/journal.pone.0125597
PMCID: PMC4418746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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