Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cerebrospinal fluid sphingolipids, β-amyloid, and tau in adults at risk for Alzheimer's disease.

Neurobiology of aging - 1 Nov 2014

Mielke Michelle M, Haughey Norman J, Bandaru Veera V R, Zetterberg Henrik, Blennow Kaj, Andreasson Ulf, Johnson Sterling C, Gleason Carey E, Blazel Hanna M, Puglielli Luigi, Sager Mark A, Asthana Sanjay, Carlsson Cynthia M

Abstract excerpt

Cellular studies suggest sphingolipids may cause or accelerate amyloid-beta (Aβ) and tau pathology but in vivo human studies are lacking. We determined cerebrospinal fluid levels of sphingolipids (ceramides and sphingomyelins), amyloid-beta (Aβ1-42, AβX-38, AβX-40, and AβX-42) and tau (T-tau and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Amyloid beta-Peptides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoproteins E

Share to Ceramides

Share to Cognition

Share to Sphingomyelins

Share to tau Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 24952994
DOI: 10.1016/j.neurobiolaging.2014.05.019
PMCID: PMC4170854

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24952994-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cerebrospinal fluid sphingolipids, β-amyloid, and tau in adults at risk for Alzheimer's disease.PMID 24952994Read ↗

Sphingolipid metabolism correlates with cerebrospinal fluid Beta amyloid levels in Alzheimer's disease.Semantic proximity Read ↗

Cerebrospinal fluid neutral lipids are associated with Alzheimer’s disease progressionSemantic proximity Read ↗

Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease.Semantic proximity Read ↗

Plasma lipidome dysregulation in frontotemporal dementia reveals shared, genotype-specific, and severity-linked alterationsSemantic proximity Read ↗

Particular CSF sphingolipid patterns identify iNPH and AD patientsSemantic proximity Read ↗

Cerebrospinal fluid markers for Alzheimer's disease over the lifespan: effects of age and the APOEε4 genotype.Semantic proximity Read ↗

Cerebrospinal fluid levels of phosphorylated tau and Aβ1-38/Aβ1-40/Aβ1-42 in Alzheimer's disease with PS1 mutations.Semantic proximity Read ↗

Comparison of plasma and CSF biomarkers across ethnoracial groups in the ADNISemantic proximity Read ↗

Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study.Semantic proximity Read ↗

The amyloid-β isoform pattern in cerebrospinal fluid in familial PSEN1 M139T- and L286P-associated Alzheimer's disease.Semantic proximity Read ↗

Neurodegenerative disease biomarkers Aβ1–40, Aβ1–42, tau, and p‐tau181 in the vervet monkey cerebrospinal fluid: Relation to normal aging, genetic influences, and cerebral amyloid angiopathySemantic proximity Read ↗

Increased cerebrospinal fluid A beta38/A beta42 ratio in Alzheimer disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.