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Comparison of plasma soluble and extracellular vesicles-associated biomarkers in Alzheimer’s Disease patients and cognitively normal individuals

2024-02-27

Abstract excerpt

<h4>INTRODUCTION</h4> Amyloid-β (Aβ) and tau are brain hallmarks of Alzheimer’s disease (AD) also present in blood as soluble biomarkers or encapsulated in extracellular vesicles (EVs). Our goal was to assess how soluble plasma biomarkers of AD pathology correlate with number and content of EVs. <h4>METHODS</h4> Single-molecule enzyme-linked assays were used to quantify Aβ42/40 and tau in plasma samples and neural...

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Literature Corpus work
25c53019-67f8-5e7f-8b19-42523fc38b0f
DOI
10.1101/2024.02.26.24303378
Open publication

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Comparison of plasma soluble and extracellular vesicles-associated biomarkers in Alzheimer’s Disease patients and cognitively normal individualsDOI 10.1101/2024.02.26.24303378
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