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Particular CSF sphingolipid patterns identify iNPH and AD patients

5 Sept 2018

Abstract excerpt

Idiopathic normal pressure hydrocephalus (iNPH) is characterized by reversible neurological symptoms due to an impairment in cerebrospinal fluid (CSF) clearance. In these patients, cognitive functions are severely impaired, with a scenario similar to Alzheimer's disease (AD), making the differential diagnosis difficult and highlighting the need of new markers. We analyzed the composition of sphingolipids (SLs) in...

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PMID: 30206302
DOI: 10.1038/s41598-018-31756-0

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