Article
Heat shock factor 1 prevents the reduction in thrashing due to heat shock in Caenorhabditis elegans.
Biochemical and biophysical research communications - 3 Jul 2015
Furuhashi Tsubasa, Sakamoto Kazuichi
Abstract excerpt
Heat shock factor 1 (HSF-1) is activated by heat stress and induces the expression of heat shock proteins. However, the role of HSF-1 in thermotolerance remains unclear. We previously reported that heat stress reversibly reduces thrashing movement in Caenorhabditis elegans. In this study, we analyzed the function of HSF-1 on thermotolerance by monitoring thrashing movement. hsf-1 RNAi suppressed the restoration...
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