Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heat Shock and Caloric Restriction Have a Synergistic Effect on the Heat Shock Response in a sir2.1-dependent Manner in Caenorhabditis elegans

10 Jul 2012

Abstract excerpt

The heat shock response (HSR) is responsible for maintaining cellular and organismal health through the regulation of proteostasis. Recent data demonstrating that the mammalian HSR is regulated by SIRT1 suggest that this response may be under metabolic control. To test this hypothesis, we have determined the effect of caloric restriction in Caenorhabditis elegans on activation of the HSR and have found a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22778258
DOI: 10.1074/jbc.m112.353714

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heat Shock and Caloric Restriction Have a Synergistic Effect on the Heat Shock Response in a sir2.1-dependent Manner in Caenorhabditis elegansPMID 22778258Read ↗

Transcriptomic and chromatin accessibility profiling unveils new regulators of heat hormesis in <i>Caenorhabditis elegans</i>Semantic proximity Read ↗

Age‐dependent heat shock hormesis to HSF ‐1 deficiency suggests a compensatory mechanism mediated by the unfolded protein response and innate immunity in young Caenorhabditis elegansSemantic proximity Read ↗

Dietary restriction suppresses proteotoxicity and enhances longevity by an <i>hsf‐1</i> ‐dependent mechanism in <i>Caenorhabditis elegans</i>Semantic proximity Read ↗

Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones.Semantic proximity Read ↗

HIF-1 is required for heat acclimation in the nematode Caenorhabditis elegans.Semantic proximity Read ↗

Regulation of aging and age-related disease by DAF-16 and heat-shock factor.Semantic proximity Read ↗

HSF-1–mediated cytoskeletal integrity determines thermotolerance and life spanSemantic proximity Read ↗

Cellular Proteomes Drive Tissue-Specific Regulation of the Heat Shock Response.Semantic proximity Read ↗

Heat-shock transcription factor (HSF)-1 pathway required for Caenorhabditis elegans immunity.Semantic proximity Read ↗

Heat shock factor functions at the convergence of the stress response and developmental pathways in Caenorhabditis elegans.Semantic proximity Read ↗

<i>Caenorhabditis elegans </i><scp>HSF</scp>‐1 is an essential nuclear protein that forms stress granule‐like structures following heat shockSemantic proximity Read ↗

Regulatory coordination between two major intracellular homeostatic systems: heat shock response and autophagy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.