Article
Regulatory mechanism of cold-inducible diapause in Caenorhabditis elegans.
Nature communications - 10 Jul 2024
Horikawa Makoto, Fukuyama Masamitsu, Antebi Adam, Mizunuma Masaki
Abstract excerpt
Temperature is a critical environmental cue that controls the development and lifespan of many animal species; however, mechanisms underlying low-temperature adaptation are poorly understood. Here, we describe cold-inducible diapause (CID), another type of diapause induced by low temperatures in Caenorhabditis elegans. A premature stop codon in heat shock factor 1 (hsf-1) triggers entry into CID at 9 °C, whereas...
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