Article
Heat shock factor functions at the convergence of the stress response and developmental pathways in Caenorhabditis elegans.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 2003
Walker Glenda A, Thompson Fiona J, Brawley Andrena, Scanlon Theresa, Devaney Eileen
Abstract excerpt
Heat shock factor (HSF) is best characterized as the transcriptional regulator of heat shock protein genes, required by all cells to survive periods of stress. Recent evidence suggests that HSF also functions to regulate the expression of genes involved in growth and development under normal physiological conditions. In this study, we used RNA interference (RNAi) assays to investigate the role of HSF in...
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