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Article

The nicotinic acetylcholine receptor alpha 4 subunit contains a functionally relevant SNP Haplotype.

BMC genetics - 2 May 2015

Eggert Marlene, Winterer Georg, Wanischeck Mario, Hoda Jean-Charles, Bertrand Daniel, Steinlein Ortrud

Abstract excerpt

BACKGROUND: Non-coding single nucleotide polymorphisms within the nicotinic acetylcholine receptor alpha 4 subunit gene (CHRNA4) are robustly associated with various neurological and behavioral phenotypes including schizophrenia, cognition and smoking. The most commonly associated polymorphisms are located in exon 5 and segregate as part of a haplotype. So far it is unknown if this haplotype is indeed functional,...

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Identifiers

PMID: 25934188
DOI: 10.1186/s12863-015-0204-1
PMCID: PMC4417232

Genes

CHRNA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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