Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic interaction between alpha4 and beta2 subunits of high affinity nicotinic receptor: analysis in schizophrenia.

Experimental brain research - 1 Sept 2006

De Luca Vincenzo, Voineskos Sophocles, Wong Greg, Kennedy James L

Abstract excerpt

Cholinergic dysfunction is one of the hypotheses for the cognitive deficits of schizophrenia. Neurocognitive deficits, which are well-described clinical features of schizophrenia, may be remediated by nicotine; therefore investigations of nicotinic receptor subtypes is of considerable clinical in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Brain Chemistry
Share to Chromosomes, Human, Pair 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 20

Share to Genetic Linkage

Share to Molecular Weight

Share to Receptors, Nicotinic

Share to Schizophrenia

Source

Identifiers

PMID: 16636791
DOI: 10.1007/s00221-006-0458-y

Genes

CHRNA4
CHRNB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16636791-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic interaction between alpha4 and beta2 subunits of high affinity nicotinic receptor: analysis in schizophrenia.PMID 16636791Read ↗

Genetic association analysis of tagging SNPs in alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes (CHRNA4 and CHRNB2) with schizophrenia in the Japanese population.Semantic proximity Read ↗

Association of alpha4beta2 nicotinic receptor and heavy smoking in schizophrenia.Semantic proximity Read ↗

Candidate gene association studies of the alpha 4 (CHRNA4) and beta 2 (CHRNB2) neuronal nicotinic acetylcholine receptor subunit genes in Alzheimer's disease.Semantic proximity Read ↗

Linkage of M5 muscarinic and alpha7-nicotinic receptor genes on 15q13 to schizophrenia.Semantic proximity Read ↗

The nicotinic acetylcholine receptor alpha 4 subunit contains a functionally relevant SNP Haplotype.Semantic proximity Read ↗

Association study of a nicotinic receptor variant with schizophrenic disorders.Semantic proximity Read ↗

A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men.Semantic proximity Read ↗

Cholinergic muscarinic M4 receptor gene polymorphisms: a potential risk factor and pharmacogenomic marker for schizophrenia.Semantic proximity Read ↗

Schizophrenia and smoking: evidence for a common neurobiological basis?Semantic proximity Read ↗

Association of nicotinic acetylcholine receptor subunit alpha 4 polymorphisms with nicotine dependence in 5500 Germans.Semantic proximity Read ↗

A novel permutation testing method implicates sixteen nicotinic acetylcholine receptor genes as risk factors for smoking in schizophrenia families.Semantic proximity Read ↗

The nicotinic receptor alpha5 coding polymorphism rs16969968 as a major target in disease: Functional dissection and remaining challenges.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.