Article
Neuronal nicotinic acetylcholine receptors: from the genetic analysis to neurological diseases.
Biochemical pharmacology - 15 Nov 2008
Steinlein O K, Bertrand D
Abstract excerpt
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated channels that mediate, in the peripheral nervous system, fast neurotransmission at the neuromuscular junction and in ganglia. Widely expressed in the central nervous system neuronal nAChRs are thought to contribute both to neurotransmission and modulation of neuronal activity. To date, eleven genes encoding for these receptors have been identified in the...
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