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Article

Association of HLA-DRB1 haplotypes with rheumatoid arthritis severity, mortality, and treatment response.

JAMA - 28 Apr 2015

Viatte Sebastien, Plant Darren, Han Buhm, Fu Bo, Yarwood Annie, Thomson Wendy, Symmons Deborah P M, Worthington Jane, Young Adam, Hyrich Kimme L, Morgan Ann W, Wilson Anthony G, Isaacs John D, Raychaudhuri Soumya, Barton Anne

Abstract excerpt

IMPORTANCE: Advances have been made in identifying genetic susceptibility loci for autoimmune diseases, but evidence is needed regarding their association with prognosis and treatment response. OBJECTIVE: To assess whether specific HLA-DRB1 haplotypes associated with rheumatoid arthritis (RA) susceptibility are also associated with radiological severity, mortality, and response to tumor necrosis factor (TNF)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25919528
DOI: 10.1001/jama.2015.3435
PMCID: PMC4928097

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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