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Article

Association of HLA-DRB1 locus with treatment response to abatacept or TNF inhibitors in patients with seropositive rheumatoid arthritis.

Scientific reports - 21 Mar 2024

Cha Soojin, Bang So-Young, Joo Young Bin, Cho Soo-Kyung, Choi Chan-Bum, Sung Yoon-Kyoung, Kim Tae-Hwan, Jun Jae-Bum, Yoo Dae Hyun, Lee Hye-Soon, Bae Sang-Cheol

Abstract excerpt

The strongest genetic risk factor for rheumatoid arthritis (RA) has been known as HLA-DRB1 based on amino acid positions 11, 71, and 74. This study analyzed the association between specific HLA-DRB1 locus and treatment response to abatacept or TNF inhibitors (TNFi) in patients with seropositive RA. A total of 374 Korean RA patients were treated with abatacept (n = 110) or TNFi (n = 264). Associations between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Arthritis, Rheumatoid

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Identifiers

PMID: 38514707
DOI: 10.1038/s41598-024-56987-2
PMCID: PMC10957942

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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