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Article

PADI4 and HLA-DRB1 are genetic risks for radiographic progression in RA patients, independent of ACPA status: results from the IORRA cohort study.

PloS one - 1 Jan 2013

Suzuki Taku, Ikari Katsunori, Yano Koichiro, Inoue Eisuke, Toyama Yoshiaki, Taniguchi Atsuo, Yamanaka Hisashi, Momohara Shigeki

Abstract excerpt

INTRODUCTION: Rheumatoid arthritis (RA) is a systemic, chronic inflammatory disease influenced by both genetic and environmental factors, leading to joint destruction and functional impairment. Recently, a large-scaled GWAS meta-analysis using more than 37,000 Japanese samples were conducted and 13 RA susceptibility loci were identified. However, it is not clear whether these loci have significant impact on joint...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23577190
DOI: 10.1371/journal.pone.0061045
PMCID: PMC3620057

Genes

PADI4
ANXA3
CCR6
CSF2
NFKBIE
PLD4
PTPN2
TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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PADI4 and HLA-DRB1 are genetic risks for radiographic progression in RA patients, independent of ACPA status: results from the IORRA cohort study.PMID 23577190Read ↗

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