Article
Association of the CCR5Δ32 Mutant Genotype with Sickle Cell Disease in Egyptian Patients.
Hemoglobin - 1 Jan 2000
El Sissy Maha H, Hafez Ahmed A, Moneim Sherif E A, Eldemerdash Doaa M
Abstract excerpt
Sickle cell disease is considered the most common single base mutation in the world, with >250,000 new patients being discovered each year. It consists of a wide spectrum of clinical presentations and complications. The CCR5Δ32 is the mutant genotype of C-C chemokine receptor 5 (CCR5). It is widely distributed due to several micro organisms that target macrophages in different populations. Theoretically, CCR5Δ32...
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