Article
The Dual Role of CCR5 in the Course of Influenza Infection: Exploring Treatment Opportunities.
Frontiers in immunology - 1 Jan 2021
Ferrero Maximiliano Ruben, Tavares Luciana Pádua, Garcia Cristiana Couto
Abstract excerpt
Influenza is one of the most relevant respiratory viruses to human health causing annual epidemics, and recurrent pandemics. Influenza disease is principally associated with inappropriate activation of the immune response. Chemokine receptor 5 (CCR5) and its cognate chemokines CCL3, CCL4 and CCL5 are rapidly induced upon influenza infection, contributing to leukocyte recruitment into the airways and a consequent...
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