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Article

Association of the rs1801133 variant in the MTHFR gene and sporadic Parkinson's disease.

Folia neuropathologica - 1 Jan 2015

García S, Coral-Vázquez Rm, Gallegos-Arreola M P, Montes-Almanza L A, Canto P, García-Martínez F A, Chavira-Hernández G, Palma-Flores C, Dávila-Maldonado L, Cuevas-García C F, López Hernández L B

Abstract excerpt

The MTHFR gene has been reported as a susceptibility locus for sporadic Parkinson's disease (sPD). The functional variant rs1801133 has been linked to hyperhomocysteinemia and dopaminergic cell death. Among different populations, Mexican-Mestizos (most present-day Mexicans) have the highest frequency of this variant. Therefore, we sought to determine a possible association of rs1801133 with SPD. In total, 356...

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Source

Identifiers

PMID: 25909872
DOI: 10.5114/fn.2015.49971

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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