The rs3857059 variant of the SNCA gene is associated with Parkinson's disease in Mexican Mestizos.

doi:10.1590/0004-282X20160061

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Article

The rs3857059 variant of the SNCA gene is associated with Parkinson's disease in Mexican Mestizos.

Arquivos de neuro-psiquiatria - 1 Jun 2016

García S, Chavira-Hernández G, Gallegos-Arreola M P, Dávila-Maldonado L, García Martínez F, Montes Almanza L A, Palma-Flores C, Mondragón-Terán P, Alcaraz Estrada S L, López-Hernández L B

Abstract excerpt

Among the candidate genes for Parkinson's disease (PD), SNCA has replicated association in different populations. Besides other known mutations in the SNCA gene, the rs3857059 variant has also been linked to various neurodegenerative disorders. Therefore, the aim of the present study was to search for association of this variant and sporadic PD in Mexican Mestizo patients. A case-control study was performed...

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PMID: 27332068
DOI: 10.1590/0004-282X20160061

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SNCA

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