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Article

Association of DNMT3b gene variants with sporadic Parkinson's disease in a Chinese Han population.

The journal of gene medicine - 1 Nov 2017

Chen Xiang, Xiao Yousheng, Wei Lei, Wu Yijuan, Lu Jianjun, Guo Wenyuan, Huang Shuxuan, Zhou Miaomiao, Mo Mingshu, Li Zhe, Cen Luan, Li Shaomin, Yang Chaohao, Wu Zhuohua, Hu Sophie, Pei Zhong, Yang XinLing, Qu Shaogang, Xu Pingyi

Abstract excerpt

BACKGROUND: Parkinson's disease (PD) is the second most common neurodegenerative disorder worldwide. Epigenetic modifications, specifically DNA methylation, have been implicated in the development of this disease. Genetic variants of DNA methyltransferase 3b (DNMT3b), one of the most important DNA methyltransferases, were shown to be associated with PD in a Brazilian population. However, it is unclear whether...

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Identifiers

PMID: 28990350
DOI: 10.1002/jgm.2991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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