Article
Homocysteine levels, genetic background, and cognitive impairment in Parkinson's disease.
Journal of neurology - 1 Jan 2023
Periñán María Teresa, Macías-García Daniel, Jesús Silvia, Martín-Rodríguez Juan Francisco, Muñoz-Delgado Laura, Jimenez-Jaraba Maria Valle, Buiza-Rueda Dolores, Bonilla-Toribio Marta, Adarmes-Gómez Astrid Daniela, Gómez-Garre Pilar, Mir Pablo
Abstract excerpt
BACKGROUND: Hyperhomocysteinemia is considered an independent risk factor for cognitive impairment. OBJECTIVE: To study the correlation between homocysteine levels and cognitive impairment in patients with PD. METHODS: We conducted a case-control study that included 246 patients with PD, of whom 32 were cognitively impaired. The levels of homocysteine, folate, and vitamin B12 were measured in peripheral blood....
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