Concise Review: New Insights Into the Role of Macrophages in β-Cell Proliferation

Abstract excerpt

UNLABELLED: Diabetes mellitus can potentially be treated with islet transplantation, but additional sources of β cells are necessary to overcome the short supply of donor pancreases. Although controversy still exists, it is generally believed that the postnatal expansion of the β-cell mass is mainly through pre-existing β-cell replication. Thus, understanding the molecular mechanisms underlying the regulation of...

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