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Mechanisms of Macrophage Polarization in Insulin Signaling and Sensitivity

19 Feb 2020

Abstract excerpt

Type-2 diabetes (T2D) is a disease of two etiologies: metabolic and inflammatory. At the cross-section of these etiologies lays the phenomenon of metabolic inflammation. Whilst metabolic inflammation is characterized as systemic, a common starting point is the tissue-resident macrophage, who's successful physiological or aberrant pathological adaptation to its microenvironment determines disease course and...

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PMID: 32140136
DOI: 10.3389/fendo.2020.00062

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