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Article

Islet cell plasticity and regeneration

22 Jan 2014

Abstract excerpt

Insulin-dependent diabetes is a complex multifactorial disorder characterized by loss or dysfunction of β-cells resulting in failure of metabolic control. Even though type 1 and 2 diabetes differ in their pathogenesis, restoring β-cell function is the overarching goal for improved therapy of both diseases. This could be achieved either by cell-replacement therapy or by triggering intrinsic regenerative mechanisms...

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Identifiers

PMID: 24749056
DOI: 10.1016/j.molmet.2014.01.010

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