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Development, regeneration, and physiological expansion of functional β-cells: Cellular sources and regulators

9 Jul 2024

Abstract excerpt

Pancreatic regeneration is a complex process observed in both normal and pathological conditions. The aim of this review is to provide a comprehensive understanding of the emergence of a functionally active population of insulin-secreting β-cells in the adult pancreas. The renewal of β-cells is governed by a multifaceted interaction between cellular sources of genetic and epigenetic factors. Understanding the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39045459
DOI: 10.3389/fcell.2024.1424278

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