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Article

CRISPR immunity drives rapid phage genome evolution in Streptococcus thermophilus.

mBio - 21 Apr 2015

Paez-Espino David, Sharon Itai, Morovic Wesley, Stahl Buffy, Thomas Brian C, Barrangou Rodolphe, Banfield Jillian F

Abstract excerpt

UNLABELLED: Many bacteria rely on CRISPR-Cas systems to provide adaptive immunity against phages, predation by which can shape the ecology and functioning of microbial communities. To characterize the impact of CRISPR immunization on phage genome evolution, we performed long-term bacterium-phage (Streptococcus thermophilus-phage 2972) coevolution experiments. We found that in this species, CRISPR immunity drives...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 25900652
DOI: 10.1128/mBio.00262-15
PMCID: PMC4453577

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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