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Article

The population and evolutionary dynamics of phage and bacteria with CRISPR-mediated immunity.

PLoS genetics - 1 Jan 2013

Levin Bruce R, Moineau Sylvain, Bushman Mary, Barrangou Rodolphe

Abstract excerpt

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), together with associated genes (cas), form the CRISPR-cas adaptive immune system, which can provide resistance to viruses and plasmids in bacteria and archaea. Here, we use mathematical models, population dynamic experiments, and DNA sequence analyses to investigate the host-phage interactions in a model CRISPR-cas system, Streptococcus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23516369
DOI: 10.1371/journal.pgen.1003312
PMCID: PMC3597502

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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