Evolutionary perspectives on ageing.

doi:10.1016/j.semcdb.2017.05.013

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Article

Evolutionary perspectives on ageing.

Seminars in cell & developmental biology - 1 Oct 2017

Reichard Martin

Abstract excerpt

From an evolutionary perspective, ageing is a decrease in fitness with chronological age - expressed by an increase in mortality risk and/or decline in reproductive success and mediated by deterioration of functional performance. While this makes ageing intuitively paradoxical - detrimental to individual fitness - evolutionary theory offers answers as to why ageing has evolved. In this review, I first briefly...

Topics

Adaptation, Biological
Aging
Animals
Biological Evolution
Fertility
Genetic Pleiotropy
Germ Cells
Humans
Mutation
Rejuvenation
Reproduction

Source

Open in PubMed

Identifiers

PMID: 28554569
DOI: 10.1016/j.semcdb.2017.05.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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