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Article

The uniform-score gene set analysis for identifying common pathways associated with different diabetes traits.

BMC genomics - 23 Apr 2015

Mei Hao, Li Lianna, Liu Shijian, Jiang Fan, Griswold Michael, Mosley Thomas

Abstract excerpt

BACKGROUND: Genetic heritability and expression study have shown that different diabetes traits have common genetic components and pathways. A computationally efficient pathway analysis of GWAS results will benefit post-GWAS study of SNP associations and identification of common genetic pathways from diabetes GWAS can help to improve understanding of the disease pathogenesis. RESULTS: We proposed a uniform-score...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25898945
DOI: 10.1186/s12864-015-1515-3
PMCID: PMC4415316

Genes

FOXO4
TCF3
VSX1

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