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Article

A pathway analysis of genome-wide association study highlights novel type 2 diabetes risk pathways.

Scientific reports - 2 Oct 2017

Liu Yang, Zhao Jing, Jiang Tao, Yu Mei, Jiang Guohua, Hu Yang

Abstract excerpt

Genome-wide association studies (GWAS) have been widely used to identify common type 2 diabetes (T2D) variants. However, the known variants just explain less than 20% of the overall estimated genetic contribution to T2D. Pathway-based methods have been applied into T2D GWAS datasets to investigate the biological mechanisms and reported some novel T2D risk pathways. However, few pathways were shared in these...

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Share to Databases, Genetic
Share to Diabetes Mellitus, Type 2
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to Signal Transduction

Source

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Identifiers

PMID: 28970525
DOI: 10.1038/s41598-017-12873-8
PMCID: PMC5624908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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