Article
i-GSEA4GWAS: a web server for identification of pathways/gene sets associated with traits by applying an improved gene set enrichment analysis to genome-wide association study.
Nucleic acids research - 1 Jul 2010
Zhang Kunlin, Cui Sijia, Chang Suhua, Zhang Liuyan, Wang Jing
Abstract excerpt
Genome-wide association study (GWAS) is nowadays widely used to identify genes involved in human complex disease. The standard GWAS analysis examines SNPs/genes independently and identifies only a number of the most significant SNPs. It ignores the combined effect of weaker SNPs/genes, which leads to difficulties to explore biological function and mechanism from a systems point of view. Although gene set...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.