Article
ICSNPathway: identify candidate causal SNPs and pathways from genome-wide association study by one analytical framework.
Nucleic acids research - 1 Jul 2011
Zhang Kunlin, Chang Suhua, Cui Sijia, Guo Liyuan, Zhang Liuyan, Wang Jing
Abstract excerpt
Genome-wide association study (GWAS) is widely utilized to identify genes involved in human complex disease or some other trait. One key challenge for GWAS data interpretation is to identify causal SNPs and provide profound evidence on how they affect the trait. Currently, researches are focusing on identification of candidate causal variants from the most significant SNPs of GWAS, while there is lack of support...
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