Methylation of the oxytocin receptor gene in clinically depressed patients compared to controls: The role of OXTR rs53576 genotype.

doi:10.1016/j.jpsychires.2015.03.012

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Article

Methylation of the oxytocin receptor gene in clinically depressed patients compared to controls: The role of OXTR rs53576 genotype.

Journal of psychiatric research - 1 Jun 2015

Reiner I, Van IJzendoorn M H, Bakermans-Kranenburg M J, Bleich S, Beutel M, Frieling H

Abstract excerpt

The emerging field of epigenetics provides a biological basis for gene-environment interactions relevant to depression. We focus on DNA methylation of exon 1 and 2 of the oxytocin receptor gene (OXTR) promoter. The research aims of the current study were to compare OXTR DNA methylation of depressed patients with healthy control subjects and to investigate possible influences of the OXTR rs53576 genotype. The...

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PMID: 25890851
DOI: 10.1016/j.jpsychires.2015.03.012

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OXTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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