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Article

Associations among oxytocin receptor gene (OXTR) DNA methylation in adulthood, exposure to early life adversity, and childhood trajectories of anxiousness.

Scientific reports - 7 Aug 2017

Gouin J P, Zhou Q Q, Booij L, Boivin M, Côté S M, Hébert M, Ouellet-Morin I, Szyf M, Tremblay R E, Turecki G, Vitaro F

Abstract excerpt

Recent models propose deoxyribonucleic acid methylation of key neuro-regulatory genes as a molecular mechanism underlying the increased risk of mental disorder associated with early life adversity (ELA). The goal of this study was to examine the association of ELA with oxytocin receptor gene (OXTR) methylation among young adults. Drawing from a 21-year longitudinal cohort, we compared adulthood OXTR methylation...

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Share to Adverse Childhood Experiences
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Epigenesis, Genetic

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Source

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Identifiers

PMID: 28785027
DOI: 10.1038/s41598-017-07950-x
PMCID: PMC5547144

Genes

OXTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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