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Article

Genetic, epigenetic, and environmental factors controlling oxytocin receptor gene expression.

Clinical epigenetics - 30 Jan 2021

Danoff Joshua S, Wroblewski Kelly L, Graves Andrew J, Quinn Graham C, Perkeybile Allison M, Kenkel William M, Lillard Travis S, Parikh Hardik I, Golino Hudson F, Gregory Simon G, Carter C Sue, Bales Karen L, Connelly Jessica J

Abstract excerpt

BACKGROUND: The neuropeptide oxytocin regulates mammalian social behavior. Disruptions in oxytocin signaling are a feature of many psychopathologies. One commonly studied biomarker for oxytocin involvement in psychiatric diseases is DNA methylation at the oxytocin receptor gene (OXTR). Such studies focus on DNA methylation in two regions of OXTR, exon 3 and a region termed MT2 which overlaps exon 1 and intron 1....

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Identifiers

PMID: 33516250
DOI: 10.1186/s13148-021-01017-5
PMCID: PMC7847178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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