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Oxytocin Receptor Gene Methylation as a Molecular Marker for Severity of Depressive Symptoms in Affective Disorder Patients

2021-12-06

Abstract excerpt

<h4>Background: </h4> Oxytocin (OXT) is a neuropeptide and hormone involved in emotional functioning and also seems to play a role in moderating the stress response. Both preclinical and clinical studies point to an increased methylation status of the Oxytocin receptor (OXTR) promoter region with concomitant deficits in social, cognitive and emotional functioning. We hypothesize that methylation levels (%) of the...

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Literature Corpus work
bcf73219-7a26-5ec8-a61f-eaf50950b372
DOI
10.21203/rs.3.rs-1115325/v1
Open publication

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