Article
Optimisation of signal peptide for recombinant protein secretion in bacterial hosts.
Applied microbiology and biotechnology - 1 May 2013
Low Kheng Oon, Muhammad Mahadi Nor, Md Illias Rosli
Abstract excerpt
Escherichia coli-the powerhouse for recombinant protein production-is rapidly gaining status as a reliable and efficient host for secretory expression. An improved understanding of protein translocation processes and its mechanisms has inspired and accelerated the development of new tools and applications in this field and, in particular, a more efficient secretion signal. Several important characteristics and...
Topics
- Bacterial Proteins
- Escherichia coli
- Mutation
- Protein Transport
- Recombinant Proteins