Article
FH535 increases the radiosensitivity and reverses epithelial-to-mesenchymal transition of radioresistant esophageal cancer cell line KYSE-150R.
Journal of translational medicine - 31 Mar 2015
Su Huafang, Jin Xiance, Zhang Xuebang, Zhao Lihao, Lin Baochai, Li Lili, Fei Zhenghua, Shen Lanxiao, Fang Ya, Pan Huanle, Xie Congying
Abstract excerpt
BACKGROUND: Acquired radioresistance has significantly compromised the efficacy of radiotherapy for esophageal cancer. The purpose of this study is to investigate the roles of epithelial-mesenchymal transition (EMT) and the Wnt/β-catenin signaling pathway in the acquirement of radioresistance during the radiation treatment of esophageal cancer. METHODS: We previously established a radioresistant cell line...
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