Article

YAP1-TEAD4-DKK1 is an effective target for inhibiting radiation resistance in esophageal squamous carcinoma and activation of the pathway may be related to poor prognosis of patients

2023-06-29

Abstract excerpt

<h4>Background: </h4> The resistance to radiationtherapy is responsible for the poor prognosis of ESCC(esophageal squamous cell carcinoma). Our previous clinical study confirmed that YAP1 gene amplification is one of the poor prognostic indicators of radical chemoradiotherapy for ESCC. However, the underlying mechanism by which YAP1 mediates radio-resistance still remained poorly understood. Here we aim to explore...

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Literature Corpus work: 9588128c-4c7e-5726-aad1-f106f8161e0f
DOI: 10.21203/rs.3.rs-3111397/v1

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