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Article

Silencing of XRCC4 increases radiosensitivity of triple-negative breast cancer cells

1 Mar 2019

Abstract excerpt

Abstract Background: Radiotherapy is an important locoregional treatment, and its effect on triple-negative breast cancer (TNBC) needs to be enhanced. The aim of the present study was to investigate the potential effects of XRCC4 on radiosensitivity of TNBC. Methods: The RNAi technique was implemented to establish the TNBC stable cell line with XRCC4 knockdown. MTT assay was used to detect the effect of XRCC4...

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PMID: 30842344
DOI: 10.1042/bsr20180893

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