Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fractionated irradiation-induced EMT-like phenotype conferred radioresistance in esophageal squamous cell carcinoma.

Journal of radiation research - 1 Jul 2016

Zhang Hongfang, Luo Honglei, Jiang Zhenzhen, Yue Jing, Hou Qiang, Xie Ruifei, Wu Shixiu

Abstract excerpt

The efficacy of radiotherapy, one major treatment modality for esophageal squamous cell carcinoma (ESCC) is severely attenuated by radioresistance. Epithelial-to-mesenchymal transition (EMT) is a cellular process that determines therapy response and tumor progression. However, whether EMT is induced by ionizing radiation and involved in tumor radioresistance has been less studied in ESCC. Using multiple...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epithelial-Mesenchymal Transition
Share to Esophageal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Esophageal Squamous Cell Carcinoma

Share to Mice, Nude

Share to Neoplastic Stem Cells

Share to Radiation, Ionizing

Share to Radiation Tolerance

Share to Xenograft Model Antitumor Assays

Source

Open in PubMed Open full text

Identifiers

PMID: 27125498
DOI: 10.1093/jrr/rrw030
PMCID: PMC4973649

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fractionated irradiation-induced EMT-like phenotype conferred radioresistance in esophageal squamous cell carcinoma.PMID 27125498Read ↗

FH535 increases the radiosensitivity and reverses epithelial-to-mesenchymal transition of radioresistant esophageal cancer cell line KYSE-150R.Semantic proximity Read ↗

Single-cell RNA-seq of esophageal squamous cell carcinoma cell line with fractionated irradiation reveals radioresistant gene expression patternsSemantic proximity Read ↗

Long Non-Coding RNAs as Strategic Molecules to Augment the Radiation Therapy in Esophageal Squamous Cell CarcinomaSemantic proximity Read ↗

Non-small cell lung cancer cells survived ionizing radiation treatment display cancer stem cell and epithelial-mesenchymal transition phenotypes.Semantic proximity Read ↗

Metformin inhibits the radiation-induced invasive phenotype of esophageal squamous cell carcinoma.Semantic proximity Read ↗

YAP1-TEAD4-DKK1 is an effective target for inhibiting radiation resistance in esophageal squamous carcinoma and activation of the pathway may be related to poor prognosis of patientsSemantic proximity Read ↗

Nuclear EGFR-PKM2 axis induces cancer stem cell-like characteristics in irradiation-resistant cells.Semantic proximity Read ↗

The CD44high Subpopulation of Multifraction Irradiation-Surviving NSCLC Cells Exhibits Partial EMT-Program Activation and DNA Damage Response Depending on Their p53 StatusSemantic proximity Read ↗

YTHDF1 promotes radio-resistance and regulates the repair of DNA double-strand breaks in ESCCSemantic proximity Read ↗

Induction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer cells by ionizing radiation.Semantic proximity Read ↗

Using the esophageal cancer stem cells (CSCs) for better understanding the tumor metastasis and metastasis-associated genesSemantic proximity Read ↗

Epithelial–mesenchymal transition and cancer stem cells: A route to acquired cisplatin resistance through epigenetics in HNSCCSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.