Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

WNT3 promotes chemoresistance to 5-Fluorouracil in oral squamous cell carcinoma via activating the canonical β-catenin pathway

6 May 2024

Abstract excerpt

BACKGROUND: 5-Fluorouracil (5FU) is a primary chemotherapeutic agent used to treat oral squamous cell carcinoma (OSCC). However, the development of drug resistance has significantly limited its clinical application. Therefore, there is an urgent need to determine the mechanisms underlying drug resistance and identify effective targets. In recent years, the Wingless and Int-1 (WNT) signaling pathway has been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Hedgehog Signaling Pathway Studies
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38711026
DOI: 10.1186/s12885-024-12318-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

WNT3 promotes chemoresistance to 5-Fluorouracil in oral squamous cell carcinoma via activating the canonical β-catenin pathwayPMID 38711026Read ↗

WNT3 promotes chemoresistance to 5-Fluorouracil in oral squamous cell carcinoma via activating the canonical β-catenin pathwaySemantic proximity Read ↗

Wnt/β‑catenin signaling: Causes and treatment targets of drug resistance in colorectal cancer (Review)Semantic proximity Read ↗

Wnt Signaling and Drug Resistance in Cancer.Semantic proximity Read ↗

Inhibition of Wnt/β‐catenin signaling downregulates P‐glycoprotein and reverses multi‐drug resistance of cholangiocarcinomaSemantic proximity Read ↗

Wnt signaling in cancer: from biomarkers to targeted therapies and clinical translationSemantic proximity Read ↗

Canonical Wnt Pathway Is Involved in Chemoresistance and Cell Cycle Arrest Induction in Colon Cancer Cell Line SpheroidsSemantic proximity Read ↗

Comprehending the crosstalk between Notch, Wnt and Hedgehog signaling pathways in oral squamous cell carcinoma - clinical implicationsSemantic proximity Read ↗

Triple-negative breast cancer: understanding Wnt signaling in drug resistanceSemantic proximity Read ↗

FH535 increases the radiosensitivity and reverses epithelial-to-mesenchymal transition of radioresistant esophageal cancer cell line KYSE-150R.Semantic proximity Read ↗

5-FU promotes stemness of colorectal cancer via p53-mediated WNT/β-catenin pathway activationSemantic proximity Read ↗

FOXO3a in cancer drug resistanceSemantic proximity Read ↗

Targeting Wnt/β-Catenin Pathway for Drug TherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.