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Article

The NFKB1 polymorphism (rs4648068) is associated with the cell proliferation and motility in gastric cancer.

BMC gastroenterology - 14 Feb 2015

Chen Ying, Lu Renquan, Zheng Hui, Xiao Ran, Feng Jingjing, Wang Hongling, Gao Xiang, Guo Lin

Abstract excerpt

BACKGROUND: We have demonstrated previously that NFKB1 single nucleotide polymorphism (SNP) rs4648068 GG homozygote was associated with the increased risk of gastric cancer in Chinese Han population. In this study, we constructed the recombinant plasmid pGL3-AA, pGL3-GG, pGL3-AA-NFKB and pGL3-GG-NFKB to investigate the function of rs4648068 by cell biology experiments. METHODS: Quantitative real-time PCR was used...

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Source

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Identifiers

PMID: 25888547
DOI: 10.1186/s12876-015-0243-0
PMCID: PMC4331381

Genes

NFKB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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