Article
Nuclear factor-kappa B1 is associated with gastric cancer in a Chinese population.
Medicine - 1 Dec 2014
Hua Tang, Qinsheng Wen, Xuxia Wang, Shuguang Zhao, Ming Qin, Zhenxiong Liu, Jingjie Wang
Abstract excerpt
Activated nuclear factor-κB (NF-κB) is associated with the pathogenesis of numerous cancers, such as gastric cancer (GC). Genetic polymorphisms in the genomic region containing nuclear factor-κB1 (NFKB1) have a plausible role in modulating the risk of GC. To identify markers contributing to the genetic susceptibility to GC, we analyzed 15 single nucleotide polymorphisms (SNPs, rs28362491, rs3774932, rs1598856,...
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