Article
The functional -94 insertion/deletion ATTG polymorphism in the promoter region of NFKB1 gene increases the risk of sporadic colorectal cancer.
Cancer epidemiology - 1 Oct 2013
Mohd Suzairi Mohd Shafi'i, Tan Shing Cheng, Ahmad Aizat Abdul Aziz, Mohd Aminudin Mustapha, Siti Nurfatimah Mohd Shahpudin, Andee Zakaria Dzulkarnaen, Ankathil Ravindran
Abstract excerpt
OBJECTIVE: To investigate the allele and genotype frequencies of NFKB1 -94 ins/del ATTG (rs28720239) polymorphism and to evaluate the association between the polymorphism and colorectal cancer (CRC) risk in Malaysian population. METHODS: Genomic DNA was extracted from the peripheral blood samples of 474 study subjects, which consisted of 237 histopathologically confirmed CRC patients and an equal number of...
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