Article
Common Polymorphisms in the NFKBIA Gene and Cancer Susceptibility: A Meta-Analysis.
Medical science monitor : international medical journal of experimental and clinical research - 21 Oct 2015
Zhang Meng, Huang Junjie, Tan Xiuxiu, Bai Jian, Wang Hao, Ge Yukun, Xiong Hu, Shi Jizhou, Lu Wei, Lv Zhaojie, Liang Chaozhao
Abstract excerpt
BACKGROUND: NFKBIA encodes the inhibitors of nuclear factor-κB (NF-κB), which regulate the translation of the genes involved in the inflammatory and immune reactions. Polymorphisms (rs2233406, rs3138053, and rs696) of NFKBIA have been implicated in susceptibility to many cancer types. MATERIAL AND METHODS: To evaluate the association between polymorphisms of NFKBIA and cancer susceptibility, a meta-analysis...
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