Article
Assessment of whole-genome regression for type II diabetes.
PloS one - 1 Jan 2015
Vazquez Ana I, Klimentidis Yann C, Dhurandhar Emily J, Veturi Yogasudha C, Paérez-Rodríguez Paulino
Abstract excerpt
Lifestyle and genetic factors play a large role in the development of Type 2 Diabetes (T2D). Despite the important role of genetic factors, genetic information is not incorporated into the clinical assessment of T2D risk. We assessed and compared Whole Genome Regression methods to predict the T2D status of 5,245 subjects from the Framingham Heart Study. For evaluating each method we constructed the following set...
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