Article
Genetic markers of type 2 diabetes: Progress in genome-wide association studies and clinical application for risk prediction.
Journal of diabetes - 1 Jan 2016
Wang Xueyin, Strizich Garrett, Hu Yonghua, Wang Tao, Kaplan Robert C, Qi Qibin
Abstract excerpt
Type 2 diabetes (T2D) has become a leading public health challenge worldwide. To date, a total of 83 susceptibility loci for T2D have been identified by genome-wide association studies (GWAS). Application of meta-analysis and modern genotype imputation approaches to GWAS data from diverse ethnic populations has been key in the effort to discover T2D loci. Genetic information is expected to play a vital role in...
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