Article
A methodological perspective on genetic risk prediction studies in type 2 diabetes: recommendations for future research.
Current diabetes reports - 1 Dec 2011
Willems Sara M, Mihaescu Raluca, Sijbrands Eric J G, van Duijn Cornelia M, Janssens A Cecile J W
Abstract excerpt
Fueled by the successes of genome-wide association studies, numerous studies have investigated the predictive ability of genetic risk models in type 2 diabetes. In this paper, we review these studies from a methodological perspective, focusing on the variables included in the risk models as well as the study designs and populations investigated. We argue and show that differences in study design and...
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