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Article

Genome-wide association with diabetes-related traits in the Framingham Heart Study.

BMC medical genetics - 19 Sept 2007

Meigs James B, Manning Alisa K, Fox Caroline S, Florez Jose C, Liu Chunyu, Cupples L Adrienne, Dupuis Josée

Abstract excerpt

BACKGROUND: Susceptibility to type 2 diabetes may be conferred by genetic variants having modest effects on risk. Genome-wide fixed marker arrays offer a novel approach to detect these variants. METHODS: We used the Affymetrix 100K SNP array in 1,087 Framingham Offspring Study family members to examine genetic associations with three diabetes-related quantitative glucose traits (fasting plasma glucose (FPG),...

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Share to Cardiovascular Diseases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

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Share to Genome, Human

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Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Source

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Identifiers

PMID: 17903298
DOI: 10.1186/1471-2350-8-S1-S16
PMCID: PMC1995610

Genes

ABCC8
CAPN10
KCNJ11
MAF
PPARG

Variants

rs757110
rs757110
rs1801282

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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